There is considerable evidence that language comprehenders derive lexical-semantic meaning by mentally simulating perceptual and motor attributes of described events. However, the nature of these simulations—including the level of detail that is incorporated and contexts under which simulations occur—is not well understood. Here, we examine the effects of first- versus third-person perspective on mental simulations during sentence comprehension. First-person sentences describing physical transfer towards or away from the body modulated response latencies when responses were made along a front-back axis, consistent (...) with the action-sentence compatibility effect. This effect was not observed for third-person sentences. The ACE was observed when making responses along a left-right axis for third-person, but not first-person sentences.sentences did not show an ACE along either axis. These results show that perspective is a detail that is simulated during action sentence comprehension, and that motoric activations are flexible and affected by the pronominal perspective used in the sentence. (shrink)

There is considerable evidence that language comprehenders derive lexical‐semantic meaning by mentally simulating perceptual and motor attributes of described events. However, the nature of these simulations—including the level of detail that is incorporated and contexts under which simulations occur—is not well understood. Here, we examine the effects of first‐ versus third‐person perspective on mental simulations during sentence comprehension. First‐person sentences describing physical transfer towards or away from the body (e.g., “You threw the microphone,” “You caught the microphone”) modulated response latencies (...) when responses were made along a front‐back axis, consistent with the action‐sentence compatibility effect (ACE). This effect was not observed for third‐person sentences (“He threw the microphone,” “He caught the microphone”). The ACE was observed when making responses along a left‐right axis for third‐person, but not first‐person sentences. Abstract sentences (e.g., “He heard the message”) did not show an ACE along either axis. These results show that perspective is a detail that is simulated during action sentence comprehension, and that motoric activations are flexible and affected by the pronominal perspective used in the sentence. (shrink)

The contribution of action-perception systems of the brain to lexical semantics remains controversial. Here, we used high-definition transcranial direct current stimulation (HD-tDCS) in healthy adults to examine the role of primary (left hand motor area; HMA) and higher-order (left anterior inferior parietal lobe; aIPL) action areas in action-related word processing (action verbs and manipulable nouns) compared to non-action-related control words (non-action verbs and non-manipulable nouns). We investigated stimulation-related effects at three levels of semantic processing: subliminal, implicit, and explicit. Broadly, we (...) found that stimulation of HMA and aIPL resulted in relative facilitation of action-related language processing compared to non-action. HMA stimulation facilitated action verb processing in subliminal and implicit task contexts, suggesting that HMA helps represent action verbs even in semantically shallow tasks. HMA stimulation also facilitated manipulable noun comprehension in an explicit semantic task, suggesting that HMA contributes to manipulable noun comprehension when semantic demands are high. aIPL stimulation facilitated both manipulable noun and action verb processing during an implicit task. We suggest that both HMA and aIPL play a functional role in action semantics. HMA plays a general role in the semantics of actions and manipulable objects, while aIPL is important only when visuo-motor coordination is required for the action. (shrink)

BackgroundIn the Canadian Alliance for Healthy Hearts and Minds (CAHHM) cohort, participants underwent magnetic resonance imaging (MRI) of the brain, heart, and abdomen, that generated incidental findings (IFs). The approach to managing these unexpected results remain a complex issue. Our objectives were to describe the CAHHM policy for the management of IFs, to understand the impact of disclosing IFs to healthy research participants, and to reflect on the ethical obligations of researchers in future MRI studies.MethodsBetween 2013 and 2019, 8252 participants (...) (mean age 58 ± 9 years, 54% women) were recruited with a follow-up questionnaire administered to 909 participants (40% response rate) at 1-year. The CAHHM policy followed a restricted approach, whereby routine feedback on IFs was not provided. Only IFs of severe structural abnormalities were reported.ResultsSevere structural abnormalities occurred in 8.3% (95% confidence interval 7.7–8.9%) of participants, with the highest proportions found in the brain (4.2%) and abdomen (3.1%). The majority of participants (97%) informed of an IF reported no change in quality of life, with 3% of participants reporting that the knowledge of an IF negatively impacted their quality of life. Furthermore, 50% reported increased stress in learning about an IF, and in 95%, the discovery of an IF did not adversely impact his/her life insurance policy. Most participants (90%) would enrol in the study again and perceived the MRI scan to be beneficial, regardless of whether they were informed of IFs. While the implications of a restricted approach to IF management was perceived to be mostly positive, a degree of diagnostic misconception was present amongst participants, indicating the importance of a more thorough consent process to support participant autonomy.ConclusionThe management of IFs from research MRI scans remain a challenging issue, as participants may experience stress and a reduced quality of life when IFs are disclosed. The restricted approach to IF management in CAHHM demonstrated a fair fulfillment of the overarching ethical principles of respect for autonomy, concern for wellbeing, and justice. The approach outlined in the CAHHM policy may serve as a framework for future research studies.Clinical trial registrationhttps://clinicaltrials.gov/ct2/show/nct02220582. (shrink)

The COVID-19 pandemic has necessitated a rapid escalation in the use of telepsychiatry. Herein we revisit some of the ethical issues regarding its use, including patient benefice, distributive justice, privacy, and autonomy. Based on these considerations we would hold that telepsychiatry is a vital aspect of providing psychiatric care, and ethically should be offered as a format for treatment, likely beyond the pandemic period. Investigative and advocacy efforts will need to continue to determine its exact role within psychiatric care, and (...) expand its availability for those most in need. (shrink)

يتناول محمد حيان السمّان في كتابه في "تدبير القداسة: الحجابة والحجاب - أدب الدخول على السلطان في التراث العربي الإسلامي"، الصادر عن المركز العربي للأبحاث ودراسة السياسات، العلاقة بين السلطة السياسية والمجتمع في السياق العربي - الإسلامي، من خلال موضوع الحجابة والسلطان المحتجِب عن رعيته، والوقائع المتصلة بالقدوم على أصحاب السلطة من خلفاء وملوك وسلاطين ووزراء وغيرهم، وانتظار الإذن بلقائهم. يتألف الكتاب (407 صفحات بالقطع الوسط، موثقًا ومفهرسًا) من مدخل، وقسمين فيهما عشرة فصول. في المدخل، تأسيس وإضاءة، يعالج المؤلف مسألة (...) الحجابة والحاجب من حيث اللغة والاصطلاح، ومسألة الحجابة عند ابن خلدون من منطلق الحضارة الداعية إلى انتحال الألقاب وتمييزها، ومسألة الاستئذان الشرعي والحجابة والفرق بينهما. (shrink)

First published in 1962, Freedom and History expresses a deep concern about freedom and the way it is imperilled by misunderstandings. Professor Lewis examines works of T.H. Green and compares Green with Locke and Rousseau.

The development of transplantation technology increasingly places before society a multitude of diverse, complex ethical and legal problems. The subject is the more complex because of the various divergent interests involved. There are the interests of the donor of organs, who has a right to protection of his legal position, and those of the patient in need of an often lifesaving organ. There are also the interests of the donor’s relatives, after his death, and those of the transplantation surgeons. The (...) international dimension of transplantation technology makes the picture even more complicated. Though this article is devoted to the European situation, the problems are similar all over the world. (shrink)

For parents wanting their children to get a head start in reading, it can be a challenge to find something that will maintain their attention. Now, learning to read can become a fun and enter- taining thing to do with the help of an extraordinary cat. Join Cleo-cat-tra as she brings reading to life in the charming picture book Rhymes and Times with Cleo-cat-tra by Lucy T. Geringer and illustrated by Bernardita Cox Kollock. Rhymes and Times of Cleo-cat-tra is a (...) picture book about a special cat named Cleo-cat-tra. She is not an ordinary cat, as she cleverly rhymes about animals, people, and things she encounters inside and outside her house. The rhymes are silly which make learning a fun and creative pro- cess for kids and for parents to share. This delightful story makes use of colorful illustrations to heighten a child's imagination. Its simple text and brief sentences make reading easy for the early reader. It is also a great book for children who are learning English and can be enjoyed both at home and in school through lively interactive discussions between students and teachers. It is a book for all ages. (shrink)

Collected lectures of the author on Sufism and Islamic philosophy.

Collection of author's lectures on Sufism and Islamic philosophy.